CMT Research Update: Pediatric Ankle And Gait Function

by | May 17, 2023 | 0 comments

HNF TRIAD Academic Partner Connecticut Children’s Publishes Results of CMT Pediatric Natural History Study to Better Understand Ankle Function and Gait 

HNF-funded research sought to determine how age and CMT type affect ankle strength in children. A detailed understanding of neuropathy progression is needed to guide informed treatments to improve or prevent a decline in gait function. 

Gait analysis and range of motion strength testing were used to evaluate children with both CMT1 and CMT2. The children with CMT1 had slightly more ankle strength that continued to increase with age until it plateaued at about 13 years, while the children with CMT2 were weaker and plateaued earlier but did not seem to get weaker with age. This highlights the importance of having an in-depth understanding of gait at the individual patient level using comprehensive gait analysis, including valid and reliable strength measures.

HNF continues to fund critical Pediatric Natural History Studies for CMT in preparation for clinical trials and to improve treatment outcomes. 

Are you a parent/caregiver of a child with CMT? Please participate in pediatric CMT research by joining today!

 

Learn more on this topic

Related Blog Posts

Global Registry For Inherited Neuropathies: Your Questions Answered

Global Registry For Inherited Neuropathies: Your Questions Answered

Why are we asking you to join our registry? It’s simple. Without you, researchers won’t have the essential patient information to develop the drugs, gene therapy, and clinical trials for Charcot-Marie-Tooth and other inherited neuropathies.
This is why the Hereditary Neuropathy Foundation (HNF) created the Global Registry for Inherited Neuropathies (GRIN). The registry collects the historical, clinical, and genetic information on patients diagnosed with the various forms of inherited neuropathies to help advance therapy development for these debilitating disorders. We understand there may be some hesitation joining our registry. To help mitigate any concerns, we’ve have the answers to your most common questions.

Join the conversation

Leave a Comment

0 Comments

Submit a Comment

Your email address will not be published. Required fields are marked *

Newsletter

Join for notifications on events, campaigns, & news