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  May 9, 2008, 10:49 pm

Rx - Medications Alert

Charcot-Marie-Tooth disease, medications alert

Medications that may
aggravate or
exacerbate CMT and HNPP

Charcot-Marie-Tooth disease, Rx

A Prescription For Danger

Patients with Hereditary Neuropathies and their children should avoid the medications, substances and medical procedures in the following categories, as they have potentially dangeroius effects.

Alcoholism
(excessive alcohol may worsen neuropathy symptoms)
Anabuse
Disulfiram

AIDS
Nucleosides

Antibiotics
Chloramphenicol
Penicilin (Large IV doses)
Metronidazole

Anti-Arrhythmic
Procainamide
Propafenone

Anti-Depressants
Zimeldine
Lithium
Zoloft (Setraline)

Anti-Epileptic (Seizures)
Phenytoin
Dilantin

Cardiac Conditions
Amiodarone
  (Cordarone)
Perhexiline (Pexid)

Chemotherapy Agents
Adriamycin
Bertezomib (Velcade)
Chloramphenicol
Cisplatinum (all Platinum analogs)
Doxorubicin
Etoposide (VP-16)
Ifosfamide Nitrous
Oxide (N2O)
Interferon-a

Chemotherapy Agents (Contd.)
Misomidazole adjunct to radiation therapy(Metronidazole)
Suramin
Taxol (Paclitaxel, docetaxel)
Thalidomide
Vincristine (all Vinca alkaloids)

Dental Anesthetic(N20)
Chronic repeated inhalation

Dietry Supplements (Vitamins and herbal remedies)
Mega doses of Vitamins A, D, & B6
Valarian Root

Gout
Colchicine

Hepatitis C
Interferon-a

Hypertension
Hydralazine (Apresoline)

Infections (Vaginal)
Metronidazole (Flagyl)
Glutethimide (Doriden)

Insomnia
Glutethimide (Doriden)

Leprosy (Hansens Disease)
Dapsone

Lipid Lowering Agent
Statins (Lovastatin, Prevastatin, Simvastatin)

Pain
Dilantin

Physiatric Disorders
Lithium
Misomidazole
Zoloft

Radiation Therapy
Misonidazole

Respiratory Disorders
Almitrine

Rhematoid  Arthritis
Gold (Aurothioglucose)
Penicillamine
Leflumonide (Arava)

Sedatives
Glutethimide

Seizures
Dilantin (Phenytoin)

Sickle Cell Anemina
Sodium Cynate

Tuberculosis
Ethambutol

Urinary Tract Infections
Nitrofurantoin (Furadantin, Macrodatin, Macrobid)

Toxic Drug List compiled by the Neuromuscular Disease Center, Washington University, St Louis, Mo.
 

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